Category: c-Abl

The generally accepted catalytic mechanism for ALDOA is shown in Physique S1

The generally accepted catalytic mechanism for ALDOA is shown in Physique S1. while CF2 substitution slightly increases the binding free energy, which matches the experimental measurement. In addition, we found that NDB with two CF2 insertions, the strongest binder, is entropically driven, while others including NDA with one CF2 insertion are all enthalpically driven. This […]